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Population-scale Long-read Sequencing in the All of Us Research Program

Garimella KV, Li Q, Wertz J, Lee SK, Cunial F, Huang Y, Mostovoy Y, Lorig-Roach R, English A, Su H, Levy S, Muzny DM, Berngruber C, Danzi MC, Harvey WT, LaPlante EL, Patterson K, Rozanski AN, Schwartz S, Shifaw B, Wang Y, Wong I, Xu IRL, Zaheri S, Zuchner S, Zheng X, Dugan-Perez S, Izydorczyk M, Mehta H, Gibbs RA, Lichtenstein L, Gupta N, Lennon N, Gabriel S; All of Us Research Program Long Read Working Group; Timp W, Doheny KF, Dutka T, Musick A, Wei CL, Sedlazeck FJ, Schatz MC, Talkowski ME, Eichler EE. (2025). Population-scale Long-read Sequencing in the All of Us Research Program. medRxiv [Preprint] Oct 5:2025.10.02.25336942. doi: 10.1101/2025.10.02.25336942.

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