Sui Y, Lin J, Noyes MD, Kwon Y, Wong I, Koundinya N, Harvey WT, Wu M, Hoekzema K, Munson KM, Garcia GH, Knuth J, Wertz J, Wang T, Hennick K, Karunakaran D, Polo Prieto RA, Meyer-Schuman R, Cherry F, Pehlivan D, Suter B, Gustafson JA, Miller DE; Human Pangenome Reference Consortium (HPRC); Berk-Rauch H, Nowakowski TJ, Chakravarti A, Zoghbi HY, Eichler EE. (2026). Using the linear references from the pangenome to discover missing autism variants. Nat Commun Jan 23. doi: 10.1038/s41467-026-68378-4. Online ahead of print.
Blog Archives
Incomplete lineage sorting of segmental duplications defines the human chromosome 2 fusion site early during African great ape speciation
Yang Z, Zhang L, Jiang X, Yang X, Ma K, Yoo D, Lu Y, Zhang S, Chen J, Nie Y, Bian X, Han J, Fu L, Zhang J, Ventura M, Zhang G, Sun Q, Eichler EE, Mao Y. (2026). Incomplete lineage sorting of segmental duplications defines the human chromosome 2 fusion site early during African great ape speciation. Cell Genom Jan 14;6(1):101079. Epub 2025 Dec 2.
The human IG heavy chain constant gene locus is enriched for large structural variants and coding polymorphisms that vary among human populations.
Jana U, Rodriguez OL, Lees W, Engelbrecht E, Vanwinkle Z, Peres A, Gibson WS, Shields K, Schultze S, Dorgham A, Emery M, Deikus G, Sebra R, Eichler EE, Yaari G, Smith ML, Watson CT. (2026). The human IG heavy chain constant gene locus is enriched for large structural variants and coding polymorphisms that vary among human populations. Cell Genom Jan 14;6(1):101058. Epub 2025 Oct 27.
Epigenetic and evolutionary features of ape subterminal heterochromatin
Yoo D, Munson KM, Eichler EE. (2026). Epigenetic and evolutionary features of ape subterminal heterochromatin. Genome Res Jan 5;36(1):38–49.
